The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2015
Filed:
Oct. 17, 2014
Applicant:
Sandoz Ag, Basel, CH;
Inventors:
Alfred Rupprechter, Kundl, AT;
Michael Fuchs, Kundl, AT;
Johann Holzmann, Kundl, AT;
William Lamanna, Kundl, AT;
Christoph Posch, Kundl, AT;
Hansjorg Toll, Kundl, AT;
Robert Mayer, Kundl, AT;
Assignee:
Sandoz AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); G01N 33/68 (2006.01); G01N 21/33 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6863 (2013.01); G01N 21/33 (2013.01); G01N 2333/70578 (2013.01);
Abstract
The present invention is directed to methods for determining the relative amount of wrongly disulphide bridged TNFR2:Fc in a sample of TNFR2:Fc, a fusion protein which is used in a variety of therapeutic applications. In addition, the invention pertains to a method for purifying TNFR2:Fc using said method for determining the percentage of wrongly disulphide bridged TNFR2:Fc, and to TNFR2:Fc compositions obtained thereby.