The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2015

Filed:

Nov. 02, 2011
Applicants:

Paul Olson, St. Louis, MO (US);

Don W. Moss, Louisville, KY (US);

Inventors:

Paul Olson, St. Louis, MO (US);

Don W. Moss, Louisville, KY (US);

Assignee:

Kypha, Inc., St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); G01N 33/00 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01); G01N 33/564 (2006.01); G01N 33/558 (2006.01); G01N 33/86 (2006.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); G01N 33/558 (2013.01); G01N 33/86 (2013.01); G01N 2333/4716 (2013.01); G01N 2800/125 (2013.01); G01N 2800/26 (2013.01);
Abstract

A method for treating an individual at risk for a complement-associated disorder is provided, including: (a) obtaining a sample of a body fluid from the individual; (b) measuring a complement activation level in the sample via a point-of-care lateral flow immunoassay; (c) correlating the complement activation level in the sample to a risk of a complement-associated disorder by comparing the complement activation level in the sample to a reference level in a control, wherein a deviation in complement activation level in the sample compared to the reference level in the control indicates the individual is at risk for a complement-associated disorder; (d) selecting a treatment for the individual, based on the correlating of step (c); and (e) treating the individual with the treatment selected in accordance with step (d). Lateral flow immunoassays and a method of monitoring an individual suffering from a complement-associated disorder are also provided herein.


Find Patent Forward Citations

Loading…