The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2015

Filed:

Sep. 15, 2010
Applicants:

Nii Patterson, Chelmsford, MA (US);

Jihong Tang, Brighton, MA (US);

Jixiang Han, Maryland Heights, MO (US);

Venkata Tavva, Chikkadpally, IN;

Andrew Hertig, Cambridge, MA (US);

Zhigang Zhang, Watertown, MA (US);

Thomas Martin Ramseier, Newtown, MA (US);

Karen Bohmert-tatarev, Brookline, MA (US);

Oliver P. Peoples, Arlington, MA (US);

Kristi D. Snell, Belmont, MA (US);

Inventors:

Nii Patterson, Chelmsford, MA (US);

Jihong Tang, Brighton, MA (US);

Jixiang Han, Maryland Heights, MO (US);

Venkata Tavva, Chikkadpally, IN;

Andrew Hertig, Cambridge, MA (US);

Zhigang Zhang, Watertown, MA (US);

Thomas Martin Ramseier, Newtown, MA (US);

Karen Bohmert-Tatarev, Brookline, MA (US);

Oliver P. Peoples, Arlington, MA (US);

Kristi D. Snell, Belmont, MA (US);

Assignee:

Metabolix, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C12N 15/63 (2006.01); A01H 5/00 (2006.01); A01H 5/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8214 (2013.01); C12N 15/8257 (2013.01);
Abstract

Transgenic plants, plant material, plant cells, and genetic constructs for synthesis of biopolymers, for example polyhydroxyalkanoates ('PHA') are provided. In one embodiment, the transgenic plants synthesize polyhydroxybutyrate ('PHB'). In one embodiment the transgenic plant encodes siRNA for one or more of the genes encoding enzymes for producing PHA. In a more preferred embodiment, the siRNA expression is under the control of an inducible regulatory element. In another embodiment, the transgenic plant contains transgenes that encode expression enzymes that will degrade the polymer. In a preferred embodiment, the expression of these enzymes is under the control of a germination specific, inducible, or minimal promoter. In another embodiment, the transgenic plant contains transgenes encoding enzymes that increase carbon flow for polymer synthesis. In a preferred embodiment, these transgenes encode enzymes that increase carbon flow in the Calvin Cycle.


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