The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2015
Filed:
Jun. 05, 2012
Applicants:
Mohamed Bentires-alj, Kembs-Loechle, KR;
Nicola Aceto, Casale Monferrato, IT;
Michael Stadler, Riehen, CH;
Inventors:
Mohamed Bentires-Alj, Kembs-Loechle, KR;
Nicola Aceto, Casale Monferrato, IT;
Michael Stadler, Riehen, CH;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61P 35/04 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); C07K 16/40 (2013.01); C12Q 1/6886 (2013.01); C12Y 301/03048 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/531 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01);
Abstract
A method for treating breast cancer in a subject having a breast cancer over-expressing the 'SHP2 signature' genes, as compared to normal breast tissue samples, which method comprises the step of administering to said subject a therapeutically effective amount of a modulator of the protein tyrosine phosphatase, non-receptor type 11 (PTPN11) gene or of its gene product (Shp2).