The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2015
Filed:
Jul. 27, 2012
Applicants:
Koen Weterings, Raleigh, NC (US);
Sylvie Van Herrewege, Deinze, BE;
Inventors:
Koen Weterings, Raleigh, NC (US);
Sylvie Van Herrewege, Deinze, BE;
Assignee:
Icon Genetics GmbH, , DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/62 (2006.01); C12N 15/54 (2006.01); A61K 38/45 (2006.01); C12N 9/10 (2006.01); C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1051 (2013.01); C12N 15/8258 (2013.01); C07K 2319/01 (2013.01); C07K 2319/05 (2013.01);
Abstract
The invention provides methods for increasing the levels of bi-antennary mono- and fully galactosylated N-glycans, and for decreasing the levels of hybrid-type galactosylated N-glycans on glycoproteins produced in plants or plant cells. In addition, the invention provides methods for the production of heterologous glycoproteins with increased levels of bi-antennary mono- and fully galactosylated N-glycans, or decreased levels of hybrid-type galactosylated N-glycans in plants or plant cells.