The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2015
Filed:
Mar. 05, 2010
Hiroshi Shiku, Tsu, JP;
Hiroaki Ikeda, Tsu, JP;
Koichi Iwamura, Tsu, JP;
Junichi Mineno, Otsu, JP;
Ikunoshin Kato, Otsu, JP;
Hiroshi Shiku, Tsu, JP;
Hiroaki Ikeda, Tsu, JP;
Koichi Iwamura, Tsu, JP;
Junichi Mineno, Otsu, JP;
Ikunoshin Kato, Otsu, JP;
MIE UNIVERSITY, Mie, JP;
TAKARA BIO INC., Shiga, JP;
Abstract
Disclosed is a method for enhancing the function of a T cell, which is characterized by inhibiting the expression of programmed death-1 ligand 1 (PD-L1) and/or programmed death-1 ligand 2 (PD-L2) in the T cell. Also disclosed is a function-enhanced T cell which is produced by the function enhancement method. Further disclosed is a therapeutic agent comprising the function-enhanced T cell. The T cell can enhance an immune response to cancer, and is useful in an immunotherapy effective for cancer and the treatment or prevention of infectious diseases and autoimmune diseases.