The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2015

Filed:

Mar. 14, 2013
Applicants:

Nicolas Baurin, Arpajon, FR;

Chirstian Biel, Kelkheim, DE;

Carsten Corvey, Kelkheim, DE;

Christian Lange, Holler, DE;

Danxi LI, Skillman, NJ (US);

Vincent Mikol, Charenton-le-Pont, FR;

Anke Steinmetz, Vitry sur Seine, FR;

Ercole Rao, Moerfelden-Walldorf, DE;

Inventors:

Nicolas Baurin, Arpajon, FR;

Chirstian Biel, Kelkheim, DE;

Carsten Corvey, Kelkheim, DE;

Christian Lange, Holler, DE;

Danxi Li, Skillman, NJ (US);

Vincent Mikol, Charenton-le-Pont, FR;

Anke Steinmetz, Vitry sur Seine, FR;

Ercole Rao, Moerfelden-Walldorf, DE;

Assignee:

SANOFI, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/46 (2006.01); C07K 16/00 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
C07K 16/46 (2013.01); C07K 16/00 (2013.01); C07K 16/241 (2013.01); C07K 16/244 (2013.01); C07K 16/247 (2013.01); C07K 16/2863 (2013.01); C07K 16/2866 (2013.01); C07K 16/32 (2013.01); C07K 16/461 (2013.01); C07K 16/468 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/624 (2013.01); C07K 2317/64 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

The invention provides antibody-like binding proteins comprising four polypeptide chains that form four antigen binding sites, wherein each pair of polypeptides forming an antibody-like binding protein possesses dual variable domains having a cross-over orientation. The invention also provides methods for making such antigen-like binding proteins.


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