The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2015

Filed:

Jun. 13, 2012
Applicants:

Brad St. Croix, Frederick, MD (US);

Tony Fleming, Stow, MA (US);

Amit Chaudhary, Frederick, MD (US);

Saurabh Saha, Leawood, KS (US);

Xiaoyan Michelle Zhang, Lexington, MA (US);

Rou-fun Kwong, Cambridge, MA (US);

Mary Beth Hilton, Thurmont, MD (US);

Inventors:

Brad St. Croix, Frederick, MD (US);

Tony Fleming, Stow, MA (US);

Amit Chaudhary, Frederick, MD (US);

Saurabh Saha, Leawood, KS (US);

Xiaoyan Michelle Zhang, Lexington, MA (US);

Rou-fun Kwong, Cambridge, MA (US);

Mary Beth Hilton, Thurmont, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); C07K 16/2863 (2013.01); C07K 16/30 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/55 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01);
Abstract

Antibodies that specifically bind TEM8 protein, and conjugates thereof, are disclosed herein. In some examples the conjugates and antibodies are useful for methods of detecting and treating pathogenic angiogenesis. In other examples the conjugates and antibodies are useful for methods of detecting and treating cancer. In additional examples, the conjugates and antibodies are useful for methods of decreasing binding of Anthrax protective antigen to a cell.


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