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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9181332 B1

PDFFull Text
Date of Patent:
Nov. 10, 2015

Filed:

Nov. 15, 2012

Anti-a(β) oligomer humanized antibody

Applicant:

Kyowa Hakko Kirin Co., Ltd., Tokyo, JP;

Inventors:

Tsuguo Kubota, Tokyo, JP;

Nobuyuki Suzuki, Shizuoka, JP;

Assignee:

KYOWA HAKKO KIRIN CO., LTD, Tokyo, JP;

Attorney:

Sughrue Mion, PLLC

Primary Examiner:

Kimberly A Ballard

Int. Cl.
CPC ...
C12N 15/13 (2006.01); C12N 15/63 (2006.01); C12N 5/10 (2006.01); C07K 16/18 (2006.01); C12N 15/09 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01); C12N 5/10 (2013.01); C12N 15/09 (2013.01); C12N 15/63 (2013.01);
Abstract

An anti-Aβ oligomer humanized antibody which does not bind to Aβ monomers and specifically binds only to Aβ oligomers; an anti-cognitive dysfunction agent, an agent for treating Alzheimer's disease, an agent for suppressing formation of neuritic plaque and an inhibitor of formation of Aβ amyloid fiber comprising the antibody as an active ingredient; a method for at least one of preventing and treating cognitive dysfunction or Alzheimer's disease, comprising the step of administering the antibody; and a method for suppressing progression of Alzheimer's disease, comprising the step of administering the antibody.

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