The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2015
Filed:
Jan. 31, 2013
Osaka University, Suita-shi, Osaka, JP;
The Research Foundation for Microbial Diseases of Osaka University, Suita-shi, Osaka, JP;
Medical and Biological Laboratories Co., Ltd., Nagoya-shi, Aichi, JP;
Department of Medical Sciences, Nonthaburi, TH;
Mayo Yasugi, Suita, JP;
Motoki Kuhara, Ina, JP;
Jotika Boon-Long, Nonthaburi, TH;
Kazuhito Fujiyama, Suita, JP;
Ritsuko Koketsu, Suita, JP;
Kazuyoshi Ikuta, Suita, JP;
OSAKA UNIVERSITY, Osaka, JP;
THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES OF OSAKA UNIVERSITY, Osaka, JP;
MEDICAL AND BIOLOGICAL LABORATORIES CO., LTD., Aichi, JP;
DEPARTMENT OF MEDICAL SCIENCES MINISTRY OF PUBLIC HEALTH, Nonthaburi, TH;
Abstract
Materials and methods are provided for treating influenza B infections in humans. Anti-human influenza virus monoclonal antibodies and antigen-binding fragments thereof having a neutralization activity against a human influenza B virus are provided. Methods for producing anti-human influenza B virus monoclonal antibodies are also provided. The antibodies and antigen-binding fragments thereof can be effective against a wide range of influenza B viral strains. Methods of inhibiting or treating a human influenza B infection are provided. The anti-influenza B therapeutics can also be used to manufacture medicaments effective against influenza B infections, to detect human influenza B in a human subject, for use in pharmaceutical compositions, and for use in kits for at least one of the prevention, the treatment, and the detection of human influenza B in a human subject.