The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2015
Filed:
Jan. 08, 2010
Applicants:
Bruce M. Spiegelman, Waban, MA (US);
Shingo Kajimura, Boston, MA (US);
Inventors:
Bruce M. Spiegelman, Waban, MA (US);
Shingo Kajimura, Boston, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/63 (2006.01); C07H 21/04 (2006.01); C07K 14/47 (2006.01); C12N 5/16 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); A61K 38/00 (2013.01); C07H 21/04 (2013.01); C12N 5/16 (2013.01); C12N 15/63 (2013.01);
Abstract
The invention provides methods and compositions for inducing brown fat cell differentiation through modulation of both Prdm1β and C/EBPβ activity and/or expression. Also provided are methods for preventing or treating obesity or an obesity related disorder in a subject through stimulation of both Prdm1β and C/EBPβ expression and/or activity. Further provided are methods for identifying compounds that are capable of modulating both Prdm1β and C/EBPβ expression and/or activity.