The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2015

Filed:

Jul. 04, 2011
Applicants:

Manuela Borriello, Monza, IT;

Sabrina Pucci, Bernareggio, IT;

Luigi Piero Stasi, Monza, IT;

Lucio Rovati, Monza, IT;

Inventors:

Manuela Borriello, Monza, IT;

Sabrina Pucci, Bernareggio, IT;

Luigi Piero Stasi, Monza, IT;

Lucio Rovati, Monza, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 221/04 (2006.01); C07D 471/08 (2006.01); C07D 211/34 (2006.01); C07D 221/20 (2006.01); C07D 401/06 (2006.01); C07F 1/02 (2006.01); C07D 207/16 (2006.01); C07D 209/52 (2006.01); C07D 209/54 (2006.01); C07D 211/60 (2006.01); C07D 453/06 (2006.01); C07F 7/18 (2006.01); C07D 205/04 (2006.01);
U.S. Cl.
CPC ...
C07F 1/02 (2013.01); C07D 205/04 (2013.01); C07D 207/16 (2013.01); C07D 209/52 (2013.01); C07D 209/54 (2013.01); C07D 211/34 (2013.01); C07D 211/60 (2013.01); C07D 221/04 (2013.01); C07D 221/20 (2013.01); C07D 401/06 (2013.01); C07D 453/06 (2013.01); C07D 471/08 (2013.01); C07F 7/1852 (2013.01); C07F 7/1856 (2013.01);
Abstract

There is described a novel group of cyclic amine derivative compounds, having an EPreceptor antagonistic activity and specifically pharmaceutical compounds which are useful for the treatment or alleviation of Prostaglandin E mediated diseases. The present invention therefore relates to novel compounds which are selective antagonists of the EPsubtype of PGEreceptors with analgesic and antinflammatory activity, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments, inter alia for the treatment or alleviation of Prostaglandin E mediated diseases such as acute and chronic pain, osteoarthritis, inflammation-associated disorder as arthritis, rheumatoid arthritis, cancer, migraine and endometriosis.


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