The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2015

Filed:

May. 17, 2013
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Shawn J. Stachel, Perkasie, PA (US);

Melissa Egbertson, Ambler, PA (US);

Edward Brnardic, Lansdale, PA (US);

Kristen G. Jones, Eagleville, PA (US);

John M. Sanders, Collegeville, PA (US);

Darrell Henze, Collegeville, PA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 417/10 (2006.01); C07D 471/04 (2006.01); C07D 277/28 (2006.01); C07D 277/66 (2006.01); C07D 239/34 (2006.01); C07D 239/42 (2006.01); C07D 277/30 (2006.01); C07D 403/04 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 239/34 (2013.01); C07D 239/42 (2013.01); C07D 277/28 (2013.01); C07D 277/30 (2013.01); C07D 277/66 (2013.01); C07D 403/04 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention is directed to benzyl urea compounds, which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence may be useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor Trk-A, Trk-B and/or Trk-C.


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