The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2015
Filed:
May. 24, 2012
Kenneth A. Jacobson, Silver Spring, MD (US);
Dilip K. Tosh, Rockville, MD (US);
Kenneth A. Jacobson, Silver Spring, MD (US);
Dilip K. Tosh, Rockville, MD (US);
Abstract
Disclosed are Aadenosine receptor antagonists and/or partial agonists and Aadenosine receptor agonists and/or partial agonists of formula (I): wherein Rto Rare as described herein, as well as pharmaceutical compositions thereof and methods of use thereof. The AAR antagonists or partial agonists find use in treating a number of diseases such as cancer, glaucoma, and inflammatory diseases, as well as in preventing cardiac ischemia. Also disclosed are radiolabeled compounds of formula (I) and the use thereof in diagnostic imaging of tissues and organs. The AAR agonists and partial agonists find use in treating diseases such as seizures, convulsion, stroke, diabetes, pain, arrhythmias, depression, and anxiety and in cardioprotection or neuroprotection.