The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2015

Filed:

Oct. 05, 2012
Applicant:

Biogen Idec MA Inc., Cambridge, MA (US);

Inventors:

Richard D. Caldwell, Brookline, MA (US);

Kevin M. Guckian, Marlborough, MA (US);

Gnanasambandam Kumaravel, Lexington, MA (US);

Wen-Cherng Lee, Lexington, MA (US);

Edward Yin-Shiang Lin, Chestnut Hill, MA (US);

Xiaogao Liu, Dover, MA (US);

Bin Ma, Arlington, MA (US);

Daniel M. Scott, Weston, MA (US);

Zhan Shi, Concord, MA (US);

Jermaine Thomas, Chelsea, MA (US);

Arthur G. Taveras, Boston, MA (US);

Guo Zhu Zheng, Lexington, MA (US);

Assignee:

BIOGEN MA INC., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); C07D 215/20 (2006.01); C07C 217/74 (2006.01); C07D 215/06 (2006.01); C07D 215/227 (2006.01); C07D 233/32 (2006.01); C07D 239/74 (2006.01); C07D 277/64 (2006.01); C07D 401/04 (2006.01); C07F 9/09 (2006.01); C07F 9/60 (2006.01); C07F 9/6512 (2006.01); C07F 9/6574 (2006.01);
U.S. Cl.
CPC ...
C07D 215/227 (2013.01); C07C 217/74 (2013.01); C07D 215/06 (2013.01); C07D 233/32 (2013.01); C07D 239/74 (2013.01); C07D 277/64 (2013.01); C07D 401/04 (2013.01); C07F 9/091 (2013.01); C07F 9/60 (2013.01); C07F 9/65122 (2013.01); C07F 9/65744 (2013.01); C07C 2102/10 (2013.01);
Abstract

Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors.


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