The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2015
Filed:
Apr. 02, 2010
Pierre G. Falson, Annonay, FR;
Anthony W. Coleman, Caluire, FR;
Rachel Rima Matar Merheb, Saint Genis Laral, FR;
Antoine Leydier, Bagnols-sur-Ceze, FR;
Frederic Huche, La Ferte-Allais, FR;
Pierre G. Falson, Annonay, FR;
Anthony W. Coleman, Caluire, FR;
Rachel Rima Matar Merheb, Saint Genis Laral, FR;
Antoine Leydier, Bagnols-sur-Ceze, FR;
Frederic Huche, La Ferte-Allais, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS—, Paris, FR;
UNIVERSITE CLAUDE BERNARD LYON 1, Villeurbanne, FR;
Abstract
The present invention relates to the use and to a process involving at least one calix[n]arene derivative substituted by at least one acid functional group on the upper face and at least one aliphatic chain of variable length on the other face, as an additive for crystallization of a polar and/or positively charged molecule. The use and the process of the present invention have the advantage of enabling, facilitating and/or accelerating the crystallization of polar and/or positively charged molecules, especially of membrane proteins that are in solution or soluble, which had previously proved to be very difficult.