The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2015

Filed:

Dec. 14, 2011
Applicants:

Peter C. Van Zijl, Baltimore, MD (US);

Dmitri Artemov, Baltimore, MD (US);

Kannie Wai Yan Chan, Baltimore, MD (US);

Yoshinori Kato, Baltimore, MD (US);

Michael T. Mcmahon, Baltimore, MD (US);

Guanshu Liu, Baltimore, MD (US);

Inventors:

Peter C. Van Zijl, Baltimore, MD (US);

Dmitri Artemov, Baltimore, MD (US);

Kannie Wai Yan Chan, Baltimore, MD (US);

Yoshinori Kato, Baltimore, MD (US);

Michael T. McMahon, Baltimore, MD (US);

Guanshu Liu, Baltimore, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/10 (2006.01); A61K 31/70 (2006.01); A61B 5/055 (2006.01); G01R 33/56 (2006.01);
U.S. Cl.
CPC ...
A61K 49/10 (2013.01); A61B 5/055 (2013.01); G01R 33/5605 (2013.01);
Abstract

A method for magnetic resonance (MR) imaging or spectroscopy on a MR scanner to detect tissue physiological parameters in one or more tissue areas in a human or non-human subject includes administering to the subject a contrast enhancing physiologically tolerable amount of a sugar that is non-labeled, subjecting the subject to an MR procedure capable of generating MR signals encoding at least one tissue area in the subject in which the sugar either passes or is taken up, detecting a temporal variation in the MR signals in the at least one tissue area after the administering the sugar, determining at least one tissue-related parameter from the temporal variation, and ascertaining whether the at least one tissue-related parameter is abnormal.


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