The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2015

Filed:

Oct. 15, 2010
Applicants:

David Vincent Sheehan, Lutz, FL (US);

Roland Douglas Shytle, Largo, FL (US);

Inventors:

David Vincent Sheehan, Lutz, FL (US);

Roland Douglas Shytle, Largo, FL (US);

Assignee:

UNIVERSITY OF SOUTH FLORIDA, Tampa, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 8/41 (2006.01); C07K 14/705 (2006.01); A61K 45/06 (2006.01); A61K 31/407 (2006.01); A61K 31/55 (2006.01); A61K 31/5513 (2006.01); A61K 33/14 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 31/407 (2013.01); A61K 31/55 (2013.01); A61K 31/5513 (2013.01); A61K 33/14 (2013.01);
Abstract

The invention concerns methods of treating suicidal ideation or behavior in a subject in need thereof, comprising decreasing endogenous nicotinic acetylcholine receptor (nAChR) activity in the subject; therapeutic packages for treating suicidal ideation or behavior; and methods for determining the efficacy of a treatment for suicidal ideation or behavior. In some embodiments, the treatment methods comprise administering to the subject an effective amount of an inhibitor of a nAChR, such as a lithium compound, mecamylamine, clozapine, or asenapine.


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