The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2015
Filed:
Jan. 11, 2011
Applicants:
Susan Faas Mcknight, Old Lyme, CT (US);
Roxanne Cofiell, Glastonbury, CT (US);
Yan Yan, Cheshire, CT (US);
Inventors:
Susan Faas McKnight, Old Lyme, CT (US);
Roxanne Cofiell, Glastonbury, CT (US);
Yan Yan, Cheshire, CT (US);
Assignee:
Alexion Pharmaceuticals, Inc., Cheshire, CT (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01); C07K 16/2803 (2013.01); G01N 33/5094 (2013.01); G01N 33/57484 (2013.01); G01N 33/68 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); A61K 2039/57 (2013.01); G01N 2333/70596 (2013.01); G01N 2800/52 (2013.01);
Abstract
The present disclosure relates to anti-CD200 antibodies (e.g., variant anti-CD200 antibodies having decreased or no effector function) and to biomarkers for use in a variety of diagnostic and therapeutic methods, e.g., determining whether a human has been administered one or more of the antibodies at a dose sufficient to induce a desired immunomodulatory effect in the human and/or selecting an appropriate dosing schedule for a patient.