The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2015
Filed:
May. 08, 2014
Applicant:
Sillajen Biotherapeutics, Inc., San Francisco, CA (US);
Inventors:
David Kirn, Mill Valley, CA (US);
Caroline Breitbach, San Francisco, CA (US);
Assignee:
SillaJen Biotherapeutics, Inc., San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/76 (2015.01); A61K 31/44 (2006.01); A61K 35/768 (2015.01); A61K 31/4412 (2006.01); A61K 38/19 (2006.01);
U.S. Cl.
CPC ...
A61K 35/768 (2013.01); A61K 31/44 (2013.01); A61K 31/4412 (2013.01); A61K 38/193 (2013.01); C12N 2710/24132 (2013.01);
Abstract
Embodiments of the invention are directed methods that include a thymidine kinase deficient vaccinia virus. The methods include evaluating a tumor for reperfusion after treatment with vaccinia virus and administering an anti-angiogenic agent if reperfusion is detected.