IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9180138 B1

PDFFull Text
Date of Patent:
Nov. 10, 2015

Filed:

Apr. 02, 2012

2'-fluoronucleosides

Applicants:

Raymond F. Schinazi, Decatur, GA (US);

Dennis C. Liotta, McDonough, GA (US);

Chung K. Chu, Athens, GA (US);

J. Jeffrey Mcatee, Mobile, AL (US);

Junxing Shi, Decatur, GA (US);

Yongseok Choi, Athens, GA (US);

Kyeong Lee, Athens, GA (US);

Joon H. Hong, Athens, GA (US);

Inventors:

Raymond F. Schinazi, Decatur, GA (US);

Dennis C. Liotta, McDonough, GA (US);

Chung K. Chu, Athens, GA (US);

J. Jeffrey McAtee, Mobile, AL (US);

Junxing Shi, Decatur, GA (US);

Yongseok Choi, Athens, GA (US);

Kyeong Lee, Athens, GA (US);

Joon H. Hong, Athens, GA (US);

Assignees:

University of Georgia Research Foundation, Inc., Athens, GA (US);

Emory University, Atlanta, GA (US);

Attorney:

King & Spalding LLP

Primary Examiner:

Jezia Riley

Int. Cl.
CPC ...
A01N 61/00 (2006.01); A61K 48/00 (2006.01); A61K 31/708 (2006.01); C07D 405/04 (2006.01); C07D 473/00 (2006.01); C07H 19/06 (2006.01); C07H 19/10 (2006.01); C07H 19/16 (2006.01); A61K 31/706 (2006.01); A61K 31/7064 (2006.01); A61K 31/7068 (2006.01); A61K 31/7072 (2006.01); A61K 31/7076 (2006.01); C07H 1/00 (2006.01); C07G 3/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/708 (2013.01); A61K 31/706 (2013.01); A61K 31/7064 (2013.01); A61K 31/7068 (2013.01); A61K 31/7072 (2013.01); A61K 31/7076 (2013.01); C07D 405/04 (2013.01); C07D 473/00 (2013.01); C07H 19/06 (2013.01); C07H 19/10 (2013.01); C07H 19/16 (2013.01);
Abstract

2'-Fluoro-nucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer. The compounds have the general formulae: wherein

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