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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9180115 B1

PDFFull Text
Date of Patent:
Nov. 10, 2015

Filed:

Mar. 20, 2014

Cyclohexylamines

Applicant:

Asana Biosciences, Llc, Bridgewater, NJ (US);

Inventors:

Scott Kevin Thompson, Phoenixville, PA (US);

Roger Astbury Smith, Chester Springs, PA (US);

Sandeep Gupta, Plainsboro, NJ (US);

Tony Priestley, West Chester, PA (US);

Nicholas James Laping, Malvern, PA (US);

Ashis K. Saha, Stow, MA (US);

Sonali Rudra, Kolkata, IN;

Assignee:

Asana Biosciences, LLC, Bridgewater, NJ (US);

Attorney:

Lerner, David, Littenberg, Krumholz & Mentlik, LLP

Primary Examiner:

Dennis Heyer

Assistant Examiner:

Daniel M Podgorski

Int. Cl.
CPC ...
A61K 31/69 (2006.01); A01N 43/40 (2006.01); A01N 55/08 (2006.01); A61K 31/40 (2006.01); C07D 309/14 (2006.01); C07D 333/38 (2006.01); C07D 333/40 (2006.01); C07D 333/70 (2006.01); C07C 219/12 (2006.01); C07C 219/14 (2006.01); C07D 207/34 (2006.01); A61K 45/06 (2006.01); A61K 31/215 (2006.01); A61K 31/235 (2006.01); A61K 31/24 (2006.01); A61K 31/351 (2006.01); A61K 31/381 (2006.01); C07C 63/49 (2006.01); C07C 65/26 (2006.01); C07D 333/72 (2006.01);
U.S. Cl.
CPC ...
A61K 31/40 (2013.01); A61K 31/215 (2013.01); A61K 31/235 (2013.01); A61K 31/24 (2013.01); A61K 31/351 (2013.01); A61K 31/381 (2013.01); A61K 45/06 (2013.01); C07C 63/49 (2013.01); C07C 65/26 (2013.01); C07C 219/12 (2013.01); C07C 219/14 (2013.01); C07D 207/34 (2013.01); C07D 309/14 (2013.01); C07D 333/38 (2013.01); C07D 333/40 (2013.01); C07D 333/70 (2013.01); C07D 333/72 (2013.01); C07C 2101/14 (2013.01);
Abstract

The present application provides novel compounds and methods for preparing and using these compounds. These compounds are useful in treating pain, itch, overactive bladder and/or interstitial cystitis in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) and a TRPV1 receptor activator. In one embodiment, the TRPV1 receptor activator is lidocaine.

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