The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2015

Filed:

Mar. 03, 2006
Applicants:

Michael D. Dake, Standford, CA (US);

Jacob M. Waugh, Moutain View, CA (US);

Inventors:

Michael D. Dake, Standford, CA (US);

Jacob M. Waugh, Moutain View, CA (US);

Assignee:

REVANCE THERAPEUTICS, INC., Newark, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); A61K 39/08 (2006.01); A61K 8/64 (2006.01); A61Q 19/08 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 8/64 (2013.01); A61Q 19/08 (2013.01); A61K 9/0019 (2013.01); A61K 2800/56 (2013.01);
Abstract

Improved formulations for transdermal delivery of botulinum toxin are disclosed. The formulations include, for example, botulinum toxin non-covalently associated with a positively charged backbone having branching or efficiency groups. The formulations also include a partitioning agent, oligo-bridge, or polyanion bridge, and may optionally contain a viscosity modifying agent. The formulations are designed for topical application onto the skin of a patient and may be used to treat wrinkles, hyperhidrosis, and other health-related problems. Kits for administration are also described.


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