The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2015

Filed:

Dec. 14, 2011
Applicants:

Jens-christoph Georgi, Aachen, DE;

Manoj Narayanan, Snohomish, WA (US);

Inventors:

Jens-Christoph Georgi, Aachen, DE;

Manoj Narayanan, Snohomish, WA (US);

Assignee:

Koninklijke Philips N.V., Eindhoven, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 6/00 (2006.01); A61B 6/03 (2006.01); G01T 1/16 (2006.01);
U.S. Cl.
CPC ...
A61B 6/583 (2013.01); A61B 6/032 (2013.01); A61B 6/037 (2013.01); A61B 6/4417 (2013.01); A61B 6/461 (2013.01); A61B 6/486 (2013.01); A61B 6/503 (2013.01); A61B 6/504 (2013.01); A61B 6/507 (2013.01); A61B 6/54 (2013.01); G01T 1/16 (2013.01);
Abstract

When estimating an arterial input function or a patient under study, cross-calibration factors are generated by comparing nuclear scan data of a radioactive material (e.g., F18) and measuring a sample of the radioactive material in a gamma counter. The derived cross-calibration factors are applied to venous samples collected from the patient during a nuclear scan after infusion with a radioactive tracer, to convert gamma values counted by the gamma counter into concentration values. The concentration values are used to optimize an initial estimated input function, thereby generating an arterialized input function.


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