The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
Oct. 05, 2012
Applicants:
Mie University, Mie, JP;
Takara Bio Inc., Shiga, JP;
Inventors:
Hiroshi Shiku, Mie, JP;
Yuki Orito, Mie, JP;
Junichi Mineno, Shiga, JP;
Sachiko Okamoto, Shiga, JP;
Yasunori Amaishi, Shiga, JP;
Assignees:
MIE UNIVERSITY, Mie, JP;
TAKARA BIO INC., Shiga, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/10 (2006.01); C12N 5/0783 (2010.01); C07H 21/04 (2006.01); C07K 14/705 (2006.01); C07K 19/00 (2006.01); C12N 15/85 (2006.01); C07K 14/725 (2006.01); C07K 16/30 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); C07K 14/70596 (2013.01); C07K 16/30 (2013.01); C07K 2319/00 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01);
Abstract
Provided are a chimeric antigen receptor comprising an extracellular domain capable of binding to an antigen, a transmembrane domain and at least one intracellular domain, the chimeric antigen receptor being characterized in that an intracellular domain of a glucocorticoid-induced tumor necrosis factor receptor (GITR) is contained as the intracellular domain; a nucleic acid encoding the chimeric antigen receptor; a cell expressing the chimeric antigen receptor; and a method for producing the cell.