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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9175285 B1

PDFFull Text
Expired
Date of Patent:
Nov. 03, 2015

Filed:

Feb. 17, 2014

Potent non-urea inhibitors of soluble epdxide hydrolase

Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Donald W. Landry, New York, NY (US);

Yuli Xie, New York, NY (US);

Yidong Lu, New York, NY (US);

Gangli Gong, Elmhurst, NY (US);

Shi-Xian Deng, White Plains, NY (US);

Kirsten Alison Rinderspacher, Bronx, NY (US);

Assignee:

THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, New York, NY (US);

Attorney:

Baker Botts L.L.P.

Primary Examiner:

Timothy R Rozof

Int. Cl.
CPC ...
C12N 9/99 (2006.01); C07D 211/96 (2006.01); C07D 401/12 (2006.01); C07D 409/12 (2006.01); C07D 211/62 (2006.01); C07F 9/59 (2006.01);
U.S. Cl.
CPC ...
C12N 9/99 (2013.01); C07D 211/62 (2013.01); C07D 211/96 (2013.01); C07D 401/12 (2013.01); C07D 409/12 (2013.01); C07F 9/591 (2013.01);
Abstract

The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension.

Find Patent Forward Citations

Landry, Donald. (2015). Potent non-urea inhibitors of soluble epdxide hydrolase (U.S. Patent No. 9175285). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9175285

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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