The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2015

Filed:

Dec. 15, 2006
Applicants:

Alexander M. Harmon, Clinton, NJ (US);

Janet E. Davis, Branchburg, NJ (US);

Inventors:

Alexander M. Harmon, Clinton, NJ (US);

Janet E. Davis, Branchburg, NJ (US);

Assignee:

DePuy Synthes Products, Inc., Raynham, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 5/073 (2010.01); A61K 35/51 (2015.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0605 (2013.01); A61K 35/51 (2013.01); A61K 2035/122 (2013.01);
Abstract

Cell-based compositions and methods of their use to inhibit an adverse immune response such as graft versus host disease or rejection of transplanted tissue in a transplant recipient that is histocompatibility mismatched to the transplant donor are disclosed. The compositions and methods utilize postpartum-derived cells, such as cells derived from the placenta or umbilicus.


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