The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2015

Filed:

Oct. 07, 2013
Applicant:

University of Miami, Miami, FL (US);

Inventors:

Christopher A. Fraker, Miami, FL (US);

Juan Dominguez-Bendala, Miramar, FL (US);

Camillo Ricordi, Miami, FL (US);

Luca Inverardi, Miami, FL (US);

Assignee:

University of Miami, Miami, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); C12N 1/00 (2006.01); C12M 1/04 (2006.01); C12M 1/32 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01);
U.S. Cl.
CPC ...
C12M 23/24 (2013.01); C12M 23/12 (2013.01); C12M 23/20 (2013.01); C12M 25/04 (2013.01); C12M 29/04 (2013.01);
Abstract

Provided is a cell culture apparatus for culturing cells, that provides enhanced oxygen delivery and supply to cells without the need for stirring or sparging. Oxygen diffusion occurs on both sides of the culture vessel, top and bottom. A gas-permeable membrane that includes perfluorocarbons or fluorocarbon derivatives (e.g., fluorinated silane, partially fluorinated silane) in its composition allows for the rapid, enhanced and uniform transfer of oxygen between the environment of cells or tissues contained in the cell culture container apparatus and the atmosphere of the incubator in which the cell culture apparatus is incubated.


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