The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
Jan. 23, 2014
Applicant:
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
Inventors:
Adolfo Garcia-Sastre, New York, NY (US);
Peter Palese, New York, NY (US);
Taia T. Wang, New York, NY (US);
Assignee:
Icahn School of Medicine at Mount Sinai, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1018 (2013.01); G01N 33/56983 (2013.01); A61K 2039/505 (2013.01); C07K 2317/33 (2013.01); C07K 2317/76 (2013.01);
Abstract
Provided herein are methods of producing neutralizing monoclonal antibodies, by cyclical immunization, that cross-react with strains of Influenza virus of the same subtype or different subtypes. Also provided herein are compositions comprising such antibodies and methods of using such antibodies to diagnose, prevent or treat Influenza virus disease.