The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2015

Filed:

Nov. 04, 2004
Applicants:

Shuji Miyagawa, Ashiya, JP;

Katsuyoshi Matsunami, Hiroshima, JP;

Inventors:

Shuji Miyagawa, Ashiya, JP;

Katsuyoshi Matsunami, Hiroshima, JP;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/74 (2006.01); C12N 15/12 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70539 (2013.01); A01K 2267/02 (2013.01); C07K 2319/00 (2013.01);
Abstract

HLA-E chimeric molecules for providing nonhuman mammalian cells resistant to cytotoxic human NK cells, nucleotide sequences encoding these chimeric molecules, and nonhuman mammalian cells and nonhuman mammals transformed with such nucleotide sequences are disclosed herein. The HLA-E chimeric molecules of the invention contain a peptide that reforms all or part of the signal peptide region, α1 domain and/or α2 domain of HLA-E, and a nucleotide sequence of the invention encodes a HLA-E chimeric molecule. A transformant incorporating a nucleotide sequence of the invention expresses HLA-E efficiently.


Find Patent Forward Citations

Miyagawa, Shuji. (2015). Hla-e chimeric molecule (U.S. Patent No. 9175064). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9175064

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