The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2015

Filed:

Feb. 10, 2011
Applicants:

Jeffrey Schlom, Potomac, MD (US);

Kwong-yok Tsang, Bethesda, MD (US);

Ira H. Pastan, Potomac, MD (US);

Inventors:

Jeffrey Schlom, Potomac, MD (US);

Kwong-Yok Tsang, Bethesda, MD (US);

Ira H. Pastan, Potomac, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07K 14/82 (2006.01); C07H 21/00 (2006.01); A61K 38/08 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4748 (2013.01); A61K 38/08 (2013.01); A61K 39/0011 (2013.01); C07K 14/82 (2013.01); C12N 2799/023 (2013.01); C12N 2800/00 (2013.01); G01N 2333/70517 (2013.01);
Abstract

The PAGE4 gene is expressed in reproductive tissues, and is expressed in reproductive cancers, such as prostate cancer, uterine cancer, and testicular cancer. Immunogenic PAGE4 polypeptides are disclosed herein, as are nucleic acids encoding the immunogenic PAGE4 polypeptides, vectors including these polynucleotides, and host cells transformed with these vectors. These polypeptides, polynucleotides, vectors, and host cells can be used to induce an immune response to PAGE4. Diagnostic methods to detect PAGE4 are also described.


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