The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
Jan. 19, 2012
Applicants:
Mamoru Takaishi, Tsukuba, JP;
Tasuku Ishida, Tsukuba, JP;
Inventors:
Mamoru Takaishi, Tsukuba, JP;
Tasuku Ishida, Tsukuba, JP;
Assignee:
Eisai R&D Management Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); A61K 31/542 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); A61K 31/542 (2013.01); A61K 45/06 (2013.01);
Abstract
The present invention relates to a fused aminodihydrothiazine derivative of formula (I): wherein X is hydrogen or fluorine; R is monofluoromethyl or difluoromethyl; and pharmaceutically acceptable salts thereof; which compound has an Aβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβ and typified by Alzheimer-type dementia.