The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
Oct. 02, 2012
Applicant:
Trustees of Boston University, Boston, MA (US);
Inventors:
Scott E. Schaus, Boston, MA (US);
Ulla Hansen, Bedford, MA (US);
Joshua A. Bishop, Southborough, MA (US);
Assignee:
TRUSTEES OF BOSTON UNIVERSITY, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/00 (2006.01); C07D 491/056 (2006.01); C07D 491/147 (2006.01);
U.S. Cl.
CPC ...
C07D 491/056 (2013.01); C07D 491/147 (2013.01);
Abstract
The present invention relates generally to [1,3]dioxolo[4,5-g]quinoline-6(5H)thione and [1,3]dioxolo[4,5-g][1,2,4]triazolo[1,5-a]quinoline derivatives and/or compositions for use in inhibiting, preventing and/or treating cancer, e.g. hepatocellular carcionoma (HCC). In some embodiments, the invention relates to the use of small-molecule compounds to inhibit, prevent and/or treat expression of the transcription factor Late SV40 Factor (LSF) for treatment of HCC or other cancer types.