The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2015

Filed:

Feb. 28, 2013
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Jennifer R. Allen, Newbury Park, CA (US);

Albert Amegadzie, Moorpark, CA (US);

Kristin L. Andrews, Thousand Oaks, CA (US);

James Brown, Moorpark, CA (US);

Jian J. Chen, Camarillo, CA (US);

Ning Chen, Thousand Oaks, CA (US);

Essa Hu Harrington, Camarillo, CA (US);

Qingyian Liu, Camarillo, CA (US);

Thomas T. Nguyen, Newbury Park, CA (US);

Alexander J. Pickrell, Westlake Village, CA (US);

Wenyuan Qian, Camarillo, CA (US);

Shannon Rumfelt, Camarillo, CA (US);

Robert M. Rzasa, Ventura, CA (US);

Chester Chenguang Yuan, Newbury Park, CA (US);

Wenge Zhong, Thousand Oaks, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 419/14 (2006.01); C07D 419/12 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01); C07D 473/00 (2006.01); C07D 471/04 (2006.01); C07D 513/04 (2006.01); C07D 417/12 (2006.01); C07D 473/30 (2006.01); C07D 473/34 (2006.01); C07D 473/40 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 473/00 (2013.01); C07D 473/30 (2013.01); C07D 473/34 (2013.01); C07D 473/40 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01); C07D 519/00 (2013.01);
Abstract

Heterobicyclic compounds of Formula (I): or a pharmaceutically-acceptable salt, tautomer, or stereoisomer thereof, as defined in the specification, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, Huntington's Disease, and the like.


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