The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
Sep. 27, 2012
Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;
Ruyuan Hec Pharm Co., Ltd., Ruyuan, Guangdong, CN;
Xin Lei, Dongguan, CN;
Jinan Peng, Dongguan, CN;
Tianming Wang, Dongguan, CN;
Zhiqing Lv, Dongguan, CN;
Wan Li, Dongguan, CN;
SUNSHINE LAKE PHARMA CO., LTD., Dongguan, Guangdong, CN;
RUYUAN HEC PHARM CO., LTD., Ruyuan, Guangdong, CN;
Abstract
The present invention relates to the field of pharmaceutical chemistry. Disclosed herein is a crystalline form of azilsartan, which is substantially pure. The crystalline form is crystalline form A, form B, form C, form D, form E, form F, form G, form H, form I, form J or form K. The substantially pure crystalline forms of azilsartan of the invention generally have good properties such as high solubility, high bioavailability, good stability, long shelf life and good antistatic property. The crystalline forms of azilsartan generally exhibit an excellent performance in reducing clinical systolic blood pressure (SBP) and average 24-hour SBP. Disclosed herein are methods of preparing the substantially pure crystalline forms of azilsartan, pharmaceutical compositions comprising the crystalline forms, and preparation methods and uses thereof.