The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
Oct. 14, 2013
Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);
Hui Hong, Palo Alto, CA (US);
Xiang Xu, Foster City, CA (US);
Jiaxin Yu, Foster City, CA (US);
Rajinder Singh, Belmont, CA (US);
Ihab S. Darwish, San Carlos, CA (US);
Sambaiah Thota, Fremont, CA (US);
Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
Disclosed are carboxamide, sulfonamide and amine compounds including certain AMPK-activating piperidinylxoy-substituted 2,3-dihydro-1H-indene-1-amine compounds, as well as pharmaceutical compositions including them. One embodiment is a compound having the structure in which R, R,R,R,R,R,R, G, Q, k, v, x and y are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.