The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
May. 14, 2010
Tannishtha Reya, San Diego, CA (US);
Hyog Y. Kwon, La Jolla, CA (US);
Takahiro Ito, San Diego, CA (US);
Dong-wook Kim, Seoul, KR;
Vivian Oehler, Seattle, WA (US);
Jerald Radich, Sammamish, WA (US);
Tannishtha Reya, San Diego, CA (US);
Hyog Y. Kwon, La Jolla, CA (US);
Takahiro Ito, San Diego, CA (US);
Dong-Wook Kim, Seoul, KR;
Vivian Oehler, Seattle, WA (US);
Jerald Radich, Sammamish, WA (US);
Duke University, Durham, NC (US);
Abstract
Disclosed are methods of predicting responsiveness of a cancer cell to a tyrosine kinase inhibitor, and methods of predicting the risk of progression of a cancer cell to a more aggressive form. Also provided are methods of reducing proliferation or promoting differentiation of a cancer cell having reduced level of Numb or increased level of Msi. Further disclosed are methods of treating a mammalian subject having cancer and methods of assessing an agent for chemotherapeutic potential.