The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2015

Filed:

Jun. 02, 2014
Applicant:

The United States of America As Represented BY the Secretary, Department of Health and Human Servies, Washington, DC (US);

Inventors:

Shousun Chen Szu, Potomac, MD (US);

Zuzana Kossaczka, Bethesda, MD (US);

John B. Robbins, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 39/107 (2013.01); A61K 47/4833 (2013.01);
Abstract

The disclosure pertains to conjugates of the capsular polysaccharide ofO139, or a structurally and/or immunologically related oligo- or poly-saccharide, and a carrier. These conjugates are useful as pharmaceutical compositions and/or vaccines to induce serum antibodies which have bactericidal (vibriocidal) activity against, in particularO139, and are useful to prevent, treat and/or reduce the severity of disease caused byinfection, such as cholera. The present disclosure also relates to diagnostic tests forinfection, and/or cholera caused byinfection, using one or more of the oligo- or poly-saccharide-carrier conjugates or antibodies described above.


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