The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
Feb. 02, 2012
Nicholas M. Dean, Encinitas, CA (US);
Lincoln Krochmal, Los Gatos, CA (US);
Gregory Hardee, Del Mar, CA (US);
J. Gordon Foulkes, Encinitas, CA (US);
Niall O'donnell, Encinitas, CA (US);
Leroy Young, Wildwood, MO (US);
Mark Jewell, Eugene, OR (US);
Nicholas M. Dean, Encinitas, CA (US);
Lincoln Krochmal, Los Gatos, CA (US);
Gregory Hardee, Del Mar, CA (US);
J. Gordon Foulkes, Encinitas, CA (US);
Niall O'Donnell, Encinitas, CA (US);
Leroy Young, Wildwood, MO (US);
Mark Jewell, Eugene, OR (US);
Excaliard Pharamaceuticals, Inc., New York, NY (US);
Abstract
This invention provides methods of preventing formation of, or treating, fibrotic lesions, including skin scars such as keloids and hypertrophic scars which comprise administering to the subject by one or more injection a compound which comprises a modified oligonucleotide, such as a modified antisense oligonucleotide, siRNA, or oligodeoxyribonucleotide, which inhibits expression of protein involved in fibrosis. Dosing of the antisense using an intradermal threading technique is also described.