The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
Apr. 28, 2010
Applicants:
Oivin M. Guicherit, Belmont, MD (US);
Lee Rubin, Wellesley, MA (US);
Inventors:
Oivin M. Guicherit, Belmont, MD (US);
Lee Rubin, Wellesley, MA (US);
Assignee:
CURIS, INC., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/381 (2006.01); A61K 31/517 (2006.01); C07D 239/91 (2006.01);
U.S. Cl.
CPC ...
A61K 31/381 (2013.01); A61K 31/517 (2013.01); C07D 239/91 (2013.01);
Abstract
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting fromgain-of-function by contacting the cell with aantagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonizeactivity.