The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
Nov. 09, 2012
Chong Kun Dang Pharmaceutical Corp., Seoul, KR;
Young Nam Lee, Seoul, KR;
Ho Young Hwang, Seoul, KR;
Sang Myoung Noh, Seoul, KR;
Hee-Jeong Cho, Seoul, KR;
Ah-Reum Chae, Seoul, KR;
Ji Hee Lee, Seoul, KR;
Min Hyo Ki, Seoul, KR;
Jong Lae Lim, Seoul, KR;
Chong Kun Dang Pharmaceutical Corp., Seoul, KR;
Abstract
Disclosed is a pharmaceutical composition for gene delivery, comprising: (i) a gene; (ii) a water-soluble chitosan; (iii) a thiamine pyrophosphate or a pharmaceutically acceptable salt thereof; (iv) a protamine or a pharmaceutically acceptable salt thereof; and (v) a neutral or anionic phospholipid. The composition can introduce a gene into cells safely and effectively. Composed of non-toxic and injectable components, the composition is safe for the body and can be advantageously commercialized. Notably, it can deliver a gene at high efficiency in vivo as well as in vitro, and is stable in the blood.