The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
Jun. 30, 2009
Crystalline active ingredient microparticles, method for producing the same and use thereof in drugs
Applicants:
Detlef Grawe, Kleinromstedt, DE;
Sabine Gliesing, Jena, DE;
Robert Eilers, Jena, DE;
Inventors:
Assignee:
Jesalis Pharma GMBH, Jena, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01); A61K 31/56 (2006.01); A61P 5/00 (2006.01); C07J 53/00 (2006.01); C07J 1/00 (2006.01); C07J 7/00 (2006.01); C07J 3/00 (2006.01); A61K 9/16 (2006.01); H04R 5/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1694 (2013.01); A61K 9/1652 (2013.01); H04R 5/00 (2013.01);
Abstract
A method for producing highly crystalline and stable microparticles of an active substance with a very narrow size distribution. The microparticles being crystallized out of a suspension made of primary particles of the active substance, a solution of the active substance, a non-solvent for the active substance and inert formed pieces. The resulting microparticles hare are highly stable largely independent of the physiochemical properties of the active substance and can be especially suitable for fast release dosage forms of pharmaceuticals.