The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2015

Filed:

May. 21, 2010
Applicants:

Jérôme Lemoine, Lucenay, FR;

Arnaud Salvador, L′Ile d′Abeau, FR;

Jean-philippe Charrier, Tassin la Demi Lune, FR;

Tanguy Fortin, Bourgoin Jailleu, FR;

Inventors:

Jérôme Lemoine, Lucenay, FR;

Arnaud Salvador, L′Ile d′Abeau, FR;

Jean-Philippe Charrier, Tassin la Demi Lune, FR;

Tanguy Fortin, Bourgoin Jailleu, FR;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/34 (2006.01); C12Q 1/37 (2006.01); H01J 49/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6848 (2013.01);
Abstract

The present invention relates to a method for the quantitative detection of a target protein in a sample, in which the second-generation fragment ions are detected for providing a series of quantitative measurements, at least one of which is correlated to the amount of proteotypic peptide generated and to the amount of target protein in the sample, characterized in that the selected first-generation fragment ion having a mass (m/z)is a doubly-charged peptide having a proline and/or a histidine in position 1.


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