The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2015
Filed:
Apr. 15, 2011
Applicants:
Wulf Paschen, Durham, NC (US);
Wei Yang, Cary, NC (US);
Huaxin Sheng, Chapel Hill, NC (US);
David S. Warner, Chapel Hill, NC (US);
Inventors:
Wulf Paschen, Durham, NC (US);
Wei Yang, Cary, NC (US);
Huaxin Sheng, Chapel Hill, NC (US);
David S. Warner, Chapel Hill, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12Q 1/68 (2006.01); C12N 15/113 (2010.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12N 15/113 (2013.01); G01N 33/57484 (2013.01); C12N 2310/141 (2013.01); C12N 2330/51 (2013.01); C12Q 2600/112 (2013.01); G01N 2333/4706 (2013.01); G01N 2440/36 (2013.01); G01N 2500/10 (2013.01); G01N 2800/56 (2013.01);
Abstract
Disclosed herein are methods relating to inhibiting or reducing proliferation of a cancer cell, for treating cancer in a subject in need of treatment, predicting the risk of progression of cancer to a more aggressive cancer, and screening for cancer in a subject, that comprise detecting and/or decreasing the levels of SUMO conjugated proteins and detecting and/or interfering with SUMO conjugation.