The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2015

Filed:

Dec. 28, 2011
Applicants:

Taeghwan Hyeon, Seoul, KR;

Kun NA, Bucheon-si, KR;

Daishun Ling, Seoul, KR;

Wooram Park, Gunpo-si, KR;

Inventors:

Taeghwan Hyeon, Seoul, KR;

Kun Na, Bucheon-si, KR;

Daishun Ling, Seoul, KR;

Wooram Park, Gunpo-si, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/00 (2006.01); C08G 73/02 (2006.01); A61K 49/18 (2006.01); C08L 71/02 (2006.01); C08G 81/00 (2006.01); A61K 8/91 (2006.01);
U.S. Cl.
CPC ...
C08G 73/024 (2013.01); A61K 49/1857 (2013.01); A61K 49/1887 (2013.01); C08G 73/02 (2013.01); C08G 81/00 (2013.01); C08L 71/02 (2013.01); A61K 8/91 (2013.01); C08G 2261/128 (2013.01); C08L 2205/03 (2013.01);
Abstract

Provided are a mussel adhesive protein-mimetic dispersion stabilizing agent to disperse nanoparticles in an aqueous medium, a colloidal solution including nanoparticles dispersed and stabilized by the dispersion stabilizing agent, and a contrast agent including the colloidal solution. More particularly, the mussel adhesive protein-mimetic dispersion stabilizer is a polyethyleneimine-graft-(poly-ethyleneglycol;polyDOPA) PEI-graft-(PEG;PDOPA). The graft polymer is formed of two parts. One is polyethyleneglycol grafted with a polyethyleneime which has an affinity to an aqueous medium, and the other is polyDOPA which has an affinity to the surface of nanoparticles. Because of those characteristics, the stabilizer shows a stable dispersion of nano particles in the aqueous medium.


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