The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2015
Filed:
Mar. 26, 2012
Applicants:
Ayako Sakai, Kobe, JP;
Masahiro Kajita, Kobe, JP;
Inventors:
Ayako Sakai, Kobe, JP;
Masahiro Kajita, Kobe, JP;
Assignee:
SYSMEX CORPORATION, Hogan, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07H 1/06 (2006.01); C12N 5/16 (2006.01); C07K 16/44 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); C12N 5/163 (2013.01); G01N 33/5308 (2013.01);
Abstract
The present invention relates to a hybridoma producing an anti-methylated DNA antibody, obtained by cell fusion of an antibody-producing cell obtained from an animal immunized with an antigen containing 5'-(5-methyl-2′-deoxycytidine-3′-phospho)-2′-deoxyguanosine 3′-phosphate with a myeloma cell. The present invention also relates to a monoclonal antibody produced by the hybridoma and a method for immunoprecipitation of a methylated DNA using the antibody.