The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2015
Filed:
Sep. 26, 2012
Applicant:
Keio University, Minato-ku, Tokyo, JP;
Inventors:
Chie Kudo, Tokyo, JP;
Yutaka Kawakami, Tokyo, JP;
Assignee:
Keio University, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 31/00 (2006.01); A61K 38/17 (2006.01); A61K 38/19 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C07K 16/24 (2006.01); C07K 16/30 (2006.01); C12N 5/09 (2010.01); C12N 15/113 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); A61K 31/00 (2013.01); A61K 38/1709 (2013.01); A61K 38/1793 (2013.01); A61K 38/195 (2013.01); C07K 14/4702 (2013.01); C07K 16/18 (2013.01); C07K 16/24 (2013.01); C07K 16/30 (2013.01); C12N 5/0693 (2013.01); C12N 15/113 (2013.01); A61K 2039/505 (2013.01); C07K 2317/73 (2013.01); C12N 2310/14 (2013.01); C12N 2501/148 (2013.01); C12N 2502/1114 (2013.01); C12N 2502/1157 (2013.01); C12N 2502/30 (2013.01); C12N 2510/00 (2013.01);
Abstract
The invention features methods for inhibiting enhancement of expression of a FoxP3 gene in a cell, methods for inhibiting induction of differentiation of a cell into a regulatory T cell, methods for reducing immunosuppression, methods for stimulating tumor immunity, and methods for treating a patient with a tumor. The methods of the invention involve suppressing function of an FSTL1 protein in the cell. In the methods of the invention, function of an FSTL1 protein in the cell may be suppressed using an anti-FSTL1 antibody.