The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2015
Filed:
Sep. 21, 2010
Martina Kalle, Lund, SE;
Gopinath Kasetty, Lund, SE;
Nils Martin Malmsten, Täby, SE;
Praveen Papareddy, Lund, SE;
Artur Schmidtchen, Lund, SE;
Björn Ulrik Walse, Lund, SE;
Martina Kalle, Lund, SE;
Gopinath Kasetty, Lund, SE;
Nils Martin Malmsten, Täby, SE;
Praveen Papareddy, Lund, SE;
Artur Schmidtchen, Lund, SE;
Björn Ulrik Walse, Lund, SE;
XIMMUNE AB, Lund, SE;
Abstract
The present invention provides polypeptides comprising or consisting of an amino acid sequence derived from a naturally occurring protein which modulates blood coagulation, or a fragment, variant, fusion or derivative thereof, or a fusion of said fragment, variant or derivative thereof, for use in the treatment or prevention of inflammation and/or excessive coagulation of the blood. Related aspects of the invention provide isolated polypeptides comprising or consisting of an amino acid sequence of SEQ ID NOS: 1 to 3, or a fragment, variant, fusion or derivative thereof, or a fusion of said fragment, variant or derivative thereof, which exhibit an anti-inflammatory activity, together with isolated nucleic acid molecules, vectors and host cells for making the same. Additionally provided are pharmaceutical compositions comprising a polypeptide of the invention, as well as methods of use of the same in the treatment and/or prevention of inflammation and/or excessive coagulation.