The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2015
Filed:
Feb. 14, 2011
Applicants:
Tomikazu Sasaki, Bothell, WA (US);
Henry Chiu-yuen Lai, Seattle, WA (US);
Narendra Pal Singh, Lynnwood, WA (US);
Steve J. OH, Mill Creek, WA (US);
Inventors:
Tomikazu Sasaki, Bothell, WA (US);
Henry Chiu-Yuen Lai, Seattle, WA (US);
Narendra Pal Singh, Lynnwood, WA (US);
Steve J. Oh, Mill Creek, WA (US);
Assignee:
University of Washington, Seattle, WA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); C07K 7/02 (2006.01); A61K 38/04 (2006.01); A61K 47/48 (2006.01); B82Y 5/00 (2011.01); C07D 493/18 (2006.01); C07D 493/20 (2006.01); C07D 519/00 (2006.01); C07K 7/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 47/48246 (2013.01); A61K 47/48346 (2013.01); B82Y 5/00 (2013.01); C07D 493/18 (2013.01); C07D 493/20 (2013.01); C07D 519/00 (2013.01); C07K 7/06 (2013.01); A61K 38/00 (2013.01);
Abstract
The invention relates to covalent conjugates between endoperoxides and small peptides and organic compounds that bind to molecular cavities on the transferrin or lactoferrin receptor, and the use of compositions comprising these conjugates to treat cancer, hyperproliferative disorders, inflammatory diseases, and infections.