The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2015
Filed:
Mar. 13, 2014
Applicant:
Elitech Holding B.v., Spankeren, NL;
Inventors:
Noah Scarr, Seattle, WA (US);
Eugeny A. Lukhtanov, Bothell, WA (US);
Assignee:
ELITechGroup B.V., Spankeren, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/02 (2006.01); C07H 19/04 (2006.01); C07D 473/18 (2006.01); C07D 473/34 (2006.01); C07D 239/47 (2006.01); C07D 239/54 (2006.01); C07F 9/6561 (2006.01); C07F 9/6512 (2006.01); C07H 21/00 (2006.01); C07F 7/18 (2006.01);
U.S. Cl.
CPC ...
C07D 473/18 (2013.01); C07D 239/47 (2013.01); C07D 239/54 (2013.01); C07D 473/34 (2013.01); C07F 7/1856 (2013.01); C07F 9/65121 (2013.01); C07F 9/65616 (2013.01); C07H 21/00 (2013.01);
Abstract
Artificial nucleosides including 2-methyl-nucleobase-substituted butane-1,3-diol nucleosides are disclosed. Four different stereoisomers of such nucleosides are possible. Oligonucleotides made up of the artificial nucleosides form homoduplexes of greater stability than DNA duplexes and have a reduced ability to hybridize to DNA or RNA.